TY - JOUR
T1 - Muscle-strengthening physical activity is associated with cancer mortality
T2 - results from the 1998–2011 National Health Interview Surveys, National Death Index record linkage
AU - Siahpush, Mohamamd
AU - Farazi, Paraskevi A.
AU - Wang, Hongmei
AU - Robbins, Regina E.
AU - Singh, Gopal K.
AU - Su, Dejun
N1 - Publisher Copyright:
© 2019, Springer Nature Switzerland AG.
PY - 2019/6/1
Y1 - 2019/6/1
N2 - Purpose: To examine the association of muscle-strengthening activities (MSA) and cancer mortality. Methods: We pooled data from the 1998 to 2009 National Health Interview Survey (NHIS), which were linked to records in the National Death Index. Mortality follow-up was through 31 December 2011. Based on U.S. federal guidelines for physical activity, we dichotomized MSA and compared those who performed MSA twice a week or more to others with lower MSA. We also examined dose–response relationship of MSA frequency with cancer mortality. Hazard ratios (HR) from Cox regression were computed to estimate the association of MSA with the risk of cancer mortality. Mean follow-up was 7.9 years and the analysis sample size was 310,282. Results: Covariate-adjusted results showed that meeting the MSA guideline was associated with a 19% lower risk of cancer mortality (HR 0.81, 95% CI 0.73, 0.90). We found no evidence of a dose–response relationship between the frequency of performing MSA and cancer mortality. Conclusion: Adhering to the U.S. federal guideline for MSA is associated with lower cancer mortality. Public health programs and policy for cancer prevention and control should promote MSA to further reduce cancer mortality.
AB - Purpose: To examine the association of muscle-strengthening activities (MSA) and cancer mortality. Methods: We pooled data from the 1998 to 2009 National Health Interview Survey (NHIS), which were linked to records in the National Death Index. Mortality follow-up was through 31 December 2011. Based on U.S. federal guidelines for physical activity, we dichotomized MSA and compared those who performed MSA twice a week or more to others with lower MSA. We also examined dose–response relationship of MSA frequency with cancer mortality. Hazard ratios (HR) from Cox regression were computed to estimate the association of MSA with the risk of cancer mortality. Mean follow-up was 7.9 years and the analysis sample size was 310,282. Results: Covariate-adjusted results showed that meeting the MSA guideline was associated with a 19% lower risk of cancer mortality (HR 0.81, 95% CI 0.73, 0.90). We found no evidence of a dose–response relationship between the frequency of performing MSA and cancer mortality. Conclusion: Adhering to the U.S. federal guideline for MSA is associated with lower cancer mortality. Public health programs and policy for cancer prevention and control should promote MSA to further reduce cancer mortality.
KW - Cancer mortality
KW - Guidelines for physical activity
KW - Muscle-strengthening physical activity
KW - National Health Interview Survey
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U2 - 10.1007/s10552-019-01169-z
DO - 10.1007/s10552-019-01169-z
M3 - Article
C2 - 31004232
AN - SCOPUS:85064719591
SN - 0957-5243
VL - 30
SP - 663
EP - 670
JO - Cancer Causes and Control
JF - Cancer Causes and Control
IS - 6
ER -