In cells mutant for the rpoS gene coding the σs subunit of RNA polymerase, synthesis of antibiotic microcin C51, which is produced by Escherichia coll, is absent or extremely reduced. In experiments with a cloned promoter of the microcin operon, the σs subunit was shown to participate in regulation of transcription of plasmid genes that determine microcin synthesis.
|Original language||English (US)|
|Number of pages||3|
|State||Published - 1997|
ASJC Scopus subject areas