Myxoid chondrosarcoma with a translocation involving chromosomes 9 and 22

Steven H. Hinrichs, Mary A. Jaramillo, Paul H. Gumerlock, Murray B. Gardner, Jerry P. Lewis, Aaron E. Freeman

Research output: Contribution to journalArticlepeer-review

89 Scopus citations

Abstract

Myxoid chondrosarcoma is an uncommon neoplasm thought to be derived from mesenchymal chondrocytic cells. Although cytogenetic abnormalities have been reported in sarcomas, too few cases have been studied to determine the frequency of nonrandom chromosomal changes in mesenchymal tumors. In this article, we describe a chondrosarcoma with a nonrandom reciprocal translocation t(9;22)(q22;q11). The cellular homologue to the retrovirus transforming gene of simian sarcoma virus is located on chromosome #22, and its possible significance in this case is discussed.

Original languageEnglish (US)
Pages (from-to)219-226
Number of pages8
JournalCancer genetics and cytogenetics
Volume14
Issue number3-4
DOIs
StatePublished - Jan 15 1985
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cancer Research

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