Myxoid chondrosarcoma with a translocation involving chromosomes 9 and 22

Steven H. Hinrichs; Mary A. Jaramillo; Paul H. Gumerlock; Murray B. Gardner; Jerry P. Lewis; Aaron E. Freeman

doi:10.1016/0165-4608(85)90187-6

Myxoid chondrosarcoma with a translocation involving chromosomes 9 and 22

Steven H. Hinrichs, Mary A. Jaramillo, Paul H. Gumerlock, Murray B. Gardner, Jerry P. Lewis, Aaron E. Freeman

Research output: Contribution to journal › Article › peer-review

99 Scopus citations

Abstract

Myxoid chondrosarcoma is an uncommon neoplasm thought to be derived from mesenchymal chondrocytic cells. Although cytogenetic abnormalities have been reported in sarcomas, too few cases have been studied to determine the frequency of nonrandom chromosomal changes in mesenchymal tumors. In this article, we describe a chondrosarcoma with a nonrandom reciprocal translocation t(9;22)(q22;q11). The cellular homologue to the retrovirus transforming gene of simian sarcoma virus is located on chromosome #22, and its possible significance in this case is discussed.

Original language	English (US)
Pages (from-to)	219-226
Number of pages	8
Journal	Cancer genetics and cytogenetics
Volume	14
Issue number	3-4
DOIs	https://doi.org/10.1016/0165-4608(85)90187-6
State	Published - Jan 15 1985
Externally published	Yes

ASJC Scopus subject areas

Molecular Biology
Genetics
Cancer Research

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10.1016/0165-4608(85)90187-6

Cite this

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title = "Myxoid chondrosarcoma with a translocation involving chromosomes 9 and 22",

abstract = "Myxoid chondrosarcoma is an uncommon neoplasm thought to be derived from mesenchymal chondrocytic cells. Although cytogenetic abnormalities have been reported in sarcomas, too few cases have been studied to determine the frequency of nonrandom chromosomal changes in mesenchymal tumors. In this article, we describe a chondrosarcoma with a nonrandom reciprocal translocation t(9;22)(q22;q11). The cellular homologue to the retrovirus transforming gene of simian sarcoma virus is located on chromosome #22, and its possible significance in this case is discussed.",

author = "Hinrichs, {Steven H.} and Jaramillo, {Mary A.} and Gumerlock, {Paul H.} and Gardner, {Murray B.} and Lewis, {Jerry P.} and Freeman, {Aaron E.}",

note = "Funding Information: Supported in part by Grant 1203 ARI from the Council for Tobacco Research. We thank Dr. James Goodnight and Robert Munn for their expert assistance.",

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T1 - Myxoid chondrosarcoma with a translocation involving chromosomes 9 and 22

AU - Hinrichs, Steven H.

AU - Jaramillo, Mary A.

AU - Gumerlock, Paul H.

AU - Gardner, Murray B.

AU - Lewis, Jerry P.

AU - Freeman, Aaron E.

N1 - Funding Information: Supported in part by Grant 1203 ARI from the Council for Tobacco Research. We thank Dr. James Goodnight and Robert Munn for their expert assistance.

PY - 1985/1/15

Y1 - 1985/1/15

N2 - Myxoid chondrosarcoma is an uncommon neoplasm thought to be derived from mesenchymal chondrocytic cells. Although cytogenetic abnormalities have been reported in sarcomas, too few cases have been studied to determine the frequency of nonrandom chromosomal changes in mesenchymal tumors. In this article, we describe a chondrosarcoma with a nonrandom reciprocal translocation t(9;22)(q22;q11). The cellular homologue to the retrovirus transforming gene of simian sarcoma virus is located on chromosome #22, and its possible significance in this case is discussed.

AB - Myxoid chondrosarcoma is an uncommon neoplasm thought to be derived from mesenchymal chondrocytic cells. Although cytogenetic abnormalities have been reported in sarcomas, too few cases have been studied to determine the frequency of nonrandom chromosomal changes in mesenchymal tumors. In this article, we describe a chondrosarcoma with a nonrandom reciprocal translocation t(9;22)(q22;q11). The cellular homologue to the retrovirus transforming gene of simian sarcoma virus is located on chromosome #22, and its possible significance in this case is discussed.

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Myxoid chondrosarcoma with a translocation involving chromosomes 9 and 22

Abstract

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