Tumors of peripheral nerves and nerve sheaths are common pathologic entities that are histologically classified according to the component of the normal peripheral nerve or nerve sheath they most closely resemble. In this chapter, we present the key histologic features that allow for the diagnosis of peripheral nerve sheath tumors and include color illustrations. For completeness and differential diagnosis purposes, we discuss reactive/hyperplastic conditions in addition to benign and malignant categories and briefly address implications to clinical management. This text particularly highlights the relationship of peripheral nerve tumors to genetic conditions such as neurofibromatosis type 1 and 2, multiple endocrine neoplasia syndrome, Cowden syndrome, and Carney complex.
|Original language||English (US)|
|Title of host publication||Pain, Treatment, Injury, Disease and Future Directions|
|Number of pages||16|
|State||Published - Apr 23 2015|
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