Neural invasion in the staging of pancreatic cancer

Parviz M. Pour, Richard H. Bell, Surinder K. Batra

Research output: Contribution to journalArticle

83 Scopus citations

Abstract

The natural history of pancreatic ductal adenocarcinoma makes it one of the most malignant human diseases. Unknown etiology, lack of early symptoms, explosive outcome, short survival, and resistance to therapy are hallmarks of this cancer. Although surgery has been shown to be an effective therapeutic approach, the inevitable tendency for recurrence, even after apparently curative operation, has remained a mystery. Ironically, the reasons for this recurrence, which usually leads to the death of the patient within 1 or 2 years after surgery, have not been a focus of research. Several studies highlighting this problem and the possible explanations have been performed by Japanese investigators.

Original languageEnglish (US)
Pages (from-to)322-325
Number of pages4
JournalPancreas
Volume26
Issue number4
DOIs
StatePublished - May 2003

Keywords

  • Locoregional recurrence
  • Neural invasion
  • Pancreatic cancer

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Hepatology
  • Endocrinology

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