Neurodevelopmental outcomes of tracheoesophageal fistulas

Laura Elyce Newton, Shahab F. Abdessalam, Stephen C. Raynor, Elizabeth R. Lyden, Eric T. Rush, Howard Needelman, Robert A. Cusick

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Purpose The purpose of this study was to perform a retrospective review of tracheoesophageal fistula (TEF) patients who followed up in a state-sponsored program to assess neurodevelopmental outcomes. Methods Records were reviewed retrospectively of children who underwent TEF repair between August 2001 and June 2014. Children discharged from the neonatal intensive care unit were referred to the state-sponsored Developmental Tracking Infant Progress Statewide (TIPS) program. We reviewed TIPS assessments performed before age 24 months and noted referral for early school intervention services. Poor outcomes were defined as scores of "failure" on the screening assessment or referral for enrollment in early intervention services by 24 months. Children with TEF were compared with case-matched nonsyndromic children of similar gestational age and birth weight. Results Seventy-eight children underwent TEF repair. Thirty-eight followed up with TIPS. Survival was 93.6%. Predictors of hospital survival were Waterston classification (p = 0.001), birth weight (p = 0.027), and ventilator days (p = 0.013). LOS was the only significant predictor of referral for early intervention services (p = 0.0092) in multivariate analysis. There was a borderline significant difference in referral rate between children with TEF and controls. 52.6% of TEF patients were referred, while 34.2% of controls were referred (p = 0.071). Conclusion More than half of TEF patients experience neurodevelopmental delays requiring referral for early intervention (53%).

Original languageEnglish (US)
Pages (from-to)743-747
Number of pages5
JournalJournal of pediatric surgery
Issue number5
StatePublished - May 1 2016


  • Neurodevelopment
  • Outcomes
  • Tracheoesophageal fistula

ASJC Scopus subject areas

  • Surgery
  • Pediatrics, Perinatology, and Child Health


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