TY - JOUR
T1 - Neuroimaging of epilepsy, movement disorders, and degenerative diseases
AU - Murman, D. L.
AU - Frey, K. A.
PY - 1993
Y1 - 1993
N2 - Neuroimaging has improved the understanding, diagnosis, and management of several neurologic diseases and syndromes. Recent advances in the neuroimaging of epilepsy, movement disorders, and degenerative diseases of the nervous system are reviewed. Current research confirms that structural and functional neuroimages each provide unique, clinically useful information in these disorders. Quantification of images improves their diagnostic sensitivity and specificity. Presymptomatic or early neurochemical changes have been identified and followed longitudinally in several neurodegenerative diseases, providing a method for monitoring response to therapeutic intervention and pathophysiologic hypothesis testing. Functional activation studies and receptor-specific radioligands continue to advance our understanding of these disorders. Future methods will take increasing advantage of both the ability to measure neuropharmacological and neurochemical changes in vivo, and the ability to combine images and information obtained with distinct structural and functional neuroimaging modalities.
AB - Neuroimaging has improved the understanding, diagnosis, and management of several neurologic diseases and syndromes. Recent advances in the neuroimaging of epilepsy, movement disorders, and degenerative diseases of the nervous system are reviewed. Current research confirms that structural and functional neuroimages each provide unique, clinically useful information in these disorders. Quantification of images improves their diagnostic sensitivity and specificity. Presymptomatic or early neurochemical changes have been identified and followed longitudinally in several neurodegenerative diseases, providing a method for monitoring response to therapeutic intervention and pathophysiologic hypothesis testing. Functional activation studies and receptor-specific radioligands continue to advance our understanding of these disorders. Future methods will take increasing advantage of both the ability to measure neuropharmacological and neurochemical changes in vivo, and the ability to combine images and information obtained with distinct structural and functional neuroimaging modalities.
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U2 - 10.1097/00019052-199312000-00015
DO - 10.1097/00019052-199312000-00015
M3 - Review article
C2 - 7904884
AN - SCOPUS:0027379949
VL - 6
SP - 919
EP - 926
JO - Current Opinion in Neurology
JF - Current Opinion in Neurology
SN - 1350-7540
IS - 6
ER -