Neuroimmune metabolism: Uncovering the role of metabolic reprogramming in central nervous system disease

Lee E. Korshoj, Tammy Kielian

Research output: Contribution to journalArticlepeer-review

Abstract

The rapidly expanding field of immunometabolism has highlighted an intricate association between the metabolic pathways that program cellular pro-inflammatory versus anti-inflammatory activity. This Special Issue on Neuroimmune Metabolism showcases a growing body of work characterizing the metabolic profiles of the major CNS-resident and peripheral immune cell players in neuroinflammation, neurodegeneration, and brain injury. The review articles address the roles of glycolytic, oxidative, and lipid metabolism that are associated with beneficial or detrimental properties in various neurological conditions, address unanswered questions in the field, and discuss promising avenues for future therapeutics. (Figure presented.). Cover Image for this issue: https://doi.org/10.1111/jnc.15069.

Original languageEnglish (US)
Pages (from-to)8-13
Number of pages6
JournalJournal of Neurochemistry
Volume158
Issue number1
DOIs
StatePublished - Jul 2021

ASJC Scopus subject areas

  • Biochemistry
  • Cellular and Molecular Neuroscience

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