Neuroleptic sensitivity to clozapine in dementia with Lewy bodies

William J. Burke, Ronald F. Pfeiffer, Rodney D. McComb

Research output: Contribution to journalArticlepeer-review

72 Scopus citations


Dementia with Lewy bodies (DLB) may be one of the most common causes of dementia. It should be of particular interest to psychiatrists because halucinations are common presenting symptoms and because patients with DLB may be particularly sensitive to neuroleptics with respect to developing extrapyramidal symptoms. The authors describe 2 patients with DLB who were intolerant of clozapine, showing not extrapyramidal side effects, but an increase in confusion and behavioral symptoms.

Original languageEnglish (US)
Pages (from-to)227-229
Number of pages3
JournalJournal of Neuropsychiatry and Clinical Neurosciences
Issue number2
StatePublished - 1998

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health


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