Neurologic complications of rheumatic fever

Maximiliano A. Hawkes, Sebastián F. Ameriso

Research output: Chapter in Book/Report/Conference proceedingChapter


Sydenham chorea, also known as St. Vitus dance, is a major clinical criterion for the diagnosis of acute rheumatic fever. Clinically, it results in a combination of movement disorders and complex neuropsychiatric symptoms. Cardiac damage due to rheumatic fever may also predispose to neurologic complications later in life. Rheumatic heart disease (RHD) is associated with heart remodeling, cardiac arrhythmias, and ischemic stroke. Furthermore, chronically damaged heart valves are predisposed to infection. Septic brain embolism, a known complication of infective endocarditis, may result in brain ischemia, hemorrhage, and spread of the infection to the brain.

Original languageEnglish (US)
Title of host publicationHandbook of Clinical Neurology
PublisherElsevier B.V.
Number of pages9
StatePublished - Jan 2021
Externally publishedYes

Publication series

NameHandbook of Clinical Neurology
ISSN (Print)0072-9752
ISSN (Electronic)2212-4152


  • Cardioembolic stroke
  • Group A streptococcus
  • Rheumatic fever
  • St. Vitus dance
  • Sydenham chorea

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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