Neuroradiologic Applications of Central Nervous System SPECT

John D. Berger, Robert J. Witte, Karen P. Holdeman, Ronald S. Tikofsky, Robert S. Hellman, James R. McConnell, Richard D. Torkelson, Arun Angelo Patil

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Single photon emission computed tomography (SPECT) of the central nervous system (CNS) has many potentially useful interventional neuroradiologic applications. CNS SPECT allows easy and safe evaluation of the collateral circulation during internal carotid balloon test occlusion. The cerebrovascular distribution of intracarotid amobarbital sodium, which is used in the Wada test, can be accurately determined with simultaneous injection of a radiopharmaceutical. Easy and safe evaluation of the extent and distribution of vasospasm associated with subarachnoid hemorrhage or cerebral angiography is also possible with CNS SPECT. Images obtained after administration of acetazolamide can be compared with baseline images to evaluate cerebrovascular reserve before carotid endarterectomy. Seizure foci can be identified if peripheral intravenous injection is performed during an ictus. Thallium-201 imaging can be used to direct stereotactic brain biopsy to check for tumor recurrence. Radiologists need to familiarize themselves and their clinical colleagues with the many uses of this imaging technique.

Original languageEnglish (US)
Pages (from-to)777-785
Number of pages9
Issue number4
StatePublished - 1996


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  • Brain, blood flow, 10.91, 10.92
  • Brain, emission ct (ect), 10.12162
  • Brain, radionuclide studies, 10.12162
  • Cerebral blood vessels, emission ct (ect), 17.12162

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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