TY - JOUR
T1 - New forms of electrospun nanofiber materials for biomedical applications
AU - Chen, Shixuan
AU - John, Johnson V.
AU - McCarthy, Alec
AU - Xie, Jingwei
N1 - Funding Information:
This work was partially supported by startup funds from the University of Nebraska Medical Center (UNMC), National Institute of General Medical Science (NIGMS) and National Institute of Dental and Craniofacial Research (NIDCR) of the National Institutes of Health under Award Numbers R01GM123081 and 1R21DE027516, 2019 (FY19) Peer Reviewed Medical Research Program (PRMRP) Investigator-Inittiated Research Award under Congressionally Directed Medical Research Program (CDMRP), UNMC Regenerative Medicine Program pilot grant, Nebraska Research Initiative grant, and NE LB606.
Publisher Copyright:
© The Royal Society of Chemistry 2020.
PY - 2020/5/7
Y1 - 2020/5/7
N2 - Over the past two decades, electrospinning has emerged as an enabling nanotechnology to produce nanofiber materials for various biomedical applications. In particular, therapeutic/cellloaded nanofiber scaffolds have been widely examined in drug delivery, wound healing, and tissue repair and regeneration. However, due to the insufficient porosity, small pore size, noninjectability, and inaccurate spatial control in nanofibers of scaffolds, many efforts have been devoted to exploring new forms of nanofiber materials including expanded nanofiber scaffolds, nanofiber aerogels, short nanofibers, and nanofiber microspheres. This short review discusses the preparation and potential biomedical applications of new forms of nanofiber materials.
AB - Over the past two decades, electrospinning has emerged as an enabling nanotechnology to produce nanofiber materials for various biomedical applications. In particular, therapeutic/cellloaded nanofiber scaffolds have been widely examined in drug delivery, wound healing, and tissue repair and regeneration. However, due to the insufficient porosity, small pore size, noninjectability, and inaccurate spatial control in nanofibers of scaffolds, many efforts have been devoted to exploring new forms of nanofiber materials including expanded nanofiber scaffolds, nanofiber aerogels, short nanofibers, and nanofiber microspheres. This short review discusses the preparation and potential biomedical applications of new forms of nanofiber materials.
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U2 - 10.1039/d0tb00271b
DO - 10.1039/d0tb00271b
M3 - Review article
C2 - 32211735
AN - SCOPUS:85084270769
SN - 2050-750X
VL - 8
SP - 3733
EP - 3746
JO - Journal of Materials Chemistry B
JF - Journal of Materials Chemistry B
IS - 17
ER -