New frontiers in metabolomics: From measurement to insight

Robert Powers, Eli Riekeberg

Research output: Contribution to journalReview article

43 Scopus citations

Abstract

Metabolomics is the newest addition to the "omics" disciplines and has shown rapid growth in its application to human health research because of fundamental advancements in measurement and analysis techniques. Metabolomics has unique and proven advantages in systems biology and biomarker discovery. The next generation of analysis techniques promises even richer and more complete analysis capabilities that will enable earlier clinical diagnosis, drug refinement, and personalized medicine. A review of current advancements in methodologies and statistical analysis that are enhancing and improving the performance of metabolomics is presented along with highlights of some recent successful applications.

Original languageEnglish (US)
Article number1148
JournalF1000Research
Volume6
DOIs
StatePublished - 2017

Keywords

  • Biomarkers
  • Chemometrics
  • Dynamic Nuclear Polarization
  • Metabolomics
  • Metabonomics
  • Multiblock Analysis

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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