TY - JOUR
T1 - New insights into pri-miRNA processing and accumulation in plants
AU - Zhang, Shuxin
AU - Liu, Yuhui
AU - Yu, Bin
N1 - Publisher Copyright:
© 2015 John Wiley & Sons, Ltd.
PY - 2015/9/1
Y1 - 2015/9/1
N2 - MicroRNAs (miRNAs) regulate many biological processes such as development, metabolism, and others. They are processed from their primary transcripts called primary miRNA transcripts (pri-miRNAs) by the processor complex containing the RNAse III enzyme, DICER-LIKE1 (DCL1), in plants. Consequently, miRNA biogenesis is controlled through altering pri-miRNA accumulation and processing, which is crucial for plant development and adaptation to environmental changes. Plant pri-miRNAs are transcribed by DNA-dependent RNA polymerase II (Pol II) and their levels are determined through transcription and degradation, whereas pri-miRNA processing is affected by its structure, splicing, alternative splicing, loading to the processor and the processor activity, which involve in many accessory proteins. Here, we summarize recent progresses related to pri-miRNA transcription, stability, and processing in plants.
AB - MicroRNAs (miRNAs) regulate many biological processes such as development, metabolism, and others. They are processed from their primary transcripts called primary miRNA transcripts (pri-miRNAs) by the processor complex containing the RNAse III enzyme, DICER-LIKE1 (DCL1), in plants. Consequently, miRNA biogenesis is controlled through altering pri-miRNA accumulation and processing, which is crucial for plant development and adaptation to environmental changes. Plant pri-miRNAs are transcribed by DNA-dependent RNA polymerase II (Pol II) and their levels are determined through transcription and degradation, whereas pri-miRNA processing is affected by its structure, splicing, alternative splicing, loading to the processor and the processor activity, which involve in many accessory proteins. Here, we summarize recent progresses related to pri-miRNA transcription, stability, and processing in plants.
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U2 - 10.1002/wrna.1292
DO - 10.1002/wrna.1292
M3 - Review article
C2 - 26119101
AN - SCOPUS:84939463591
SN - 1757-7004
VL - 6
SP - 533
EP - 545
JO - Wiley Interdisciplinary Reviews: RNA
JF - Wiley Interdisciplinary Reviews: RNA
IS - 5
ER -