TY - JOUR
T1 - New insights into the mechanism of alcohol-mediated organ damage via its impact on immunity, metabolism, and repair pathways
T2 - A summary of the 2021 Alcohol and Immunology Research Interest Group (AIRIG) meeting
AU - Khair, Shanawaj
AU - Brenner, Lisa A.
AU - Koval, Michael
AU - Samuelson, Derrick
AU - Cucinello-Regland, Jessica A.
AU - Anton, Paige
AU - Piano, Mariann R.
AU - Simon, Liz
AU - Crotty, Kathryn
AU - Sharieh, Farah
AU - Travers, Jeffrey B.
AU - Singh, Vaibhav
AU - Cannon, Abigail
AU - Kim, Adam
AU - McCullough, Rebecca L.
AU - Yeligar, Samantha M.
AU - Wyatt, Todd A
AU - McMahan, Rachel H.
AU - Choudhry, Mashkoor A.
AU - Kovacs, Elizabeth J.
N1 - Publisher Copyright:
Copyright © 2022 Elsevier Inc. All rights reserved.
PY - 2022/9/1
Y1 - 2022/9/1
N2 - On November 19th, 2021, the annual Alcohol and Immunology Research Interest Group (AIRIG) meeting was held at Loyola University Chicago Health Sciences Campus in Maywood, Illinois. The 2021 meeting focused on how alcohol misuse is linked to immune system derangements, leading to tissue and organ damage, and how this research can be translated into improving treatment of alcohol-related disease. This meeting was divided into three plenary sessions: the first session focused on how alcohol misuse affects different parts of the immune system, the second session presented research on mechanisms of organ damage from alcohol misuse, and the final session highlighted research on potential therapeutic targets for treating alcohol-mediated tissue damage. Diverse areas of alcohol research were covered during the meeting, from alcohol's effect on pulmonary systems and neuroinflammation to epigenetic changes, senescence markers, and microvesicle particles. These presentations yielded a thoughtful discussion on how the findings can lead to therapeutic treatments for people suffering from alcohol-related diseases.
AB - On November 19th, 2021, the annual Alcohol and Immunology Research Interest Group (AIRIG) meeting was held at Loyola University Chicago Health Sciences Campus in Maywood, Illinois. The 2021 meeting focused on how alcohol misuse is linked to immune system derangements, leading to tissue and organ damage, and how this research can be translated into improving treatment of alcohol-related disease. This meeting was divided into three plenary sessions: the first session focused on how alcohol misuse affects different parts of the immune system, the second session presented research on mechanisms of organ damage from alcohol misuse, and the final session highlighted research on potential therapeutic targets for treating alcohol-mediated tissue damage. Diverse areas of alcohol research were covered during the meeting, from alcohol's effect on pulmonary systems and neuroinflammation to epigenetic changes, senescence markers, and microvesicle particles. These presentations yielded a thoughtful discussion on how the findings can lead to therapeutic treatments for people suffering from alcohol-related diseases.
KW - brain
KW - cardiovascular disease
KW - ethanol
KW - inflammation
KW - liver
KW - lung
KW - myopathy
KW - pneumonia
KW - skin
KW - stem cell
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U2 - 10.1016/j.alcohol.2022.05.004
DO - 10.1016/j.alcohol.2022.05.004
M3 - Review article
C2 - 35659577
AN - SCOPUS:85139374897
VL - 103
SP - 1
EP - 7
JO - Alcohol
JF - Alcohol
SN - 0741-8329
ER -