Abstract
The authors report the case of a 39-year-old sighted woman who displayed non-24-hour sleep-wake cycles following a car accident. The phase relationship between endogenous circadian markers such as plasma melatonin and 6-sulfatoxymelatonin rhythms and self-selected sleep times was abnormal. A laboratory investigation indicated that she was sensitive to bright light as a circadian synchronizer. MRI and brain CT scans were normal, but microscopic brain damage in the vicinity of the suprachiasmatic nucleus or its output pathways is plausible.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1841-1843 |
| Number of pages | 3 |
| Journal | Neurology |
| Volume | 60 |
| Issue number | 11 |
| DOIs | |
| State | Published - Jun 10 2003 |
| Externally published | Yes |
ASJC Scopus subject areas
- Clinical Neurology