Noncoding RNAs as a Cause of Cancer

Juan Cui

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


Noncoding RNAs (ncRNAs) are emerging as key regulators of tumorigenesis that control cancer-associated gene expression through microRNA-induced mRNA degradation or long ncRNA-mediated chromatin modification. They have been identified as highly promising cancer biomarkers through recent genome-wide association analysis, e.g., on single-nucleotide polymorphisms. This chapter will focus on the possible roles of ncRNA in causing cancer and review examples that also highlight the potential application of ncRNAs as diagnostic and prognostic biomarkers for cancer stratification and as therapeutic targets and agents for cancer treatment.

Original languageEnglish (US)
Title of host publicationCancer and Noncoding RNAs
Number of pages18
ISBN (Electronic)9780128110225
ISBN (Print)9780128134375
StatePublished - Jan 1 2018


  • Cancer biomarker
  • GWAS
  • MicroRNA
  • Noncoding RNA
  • SNPs

ASJC Scopus subject areas

  • General Medicine
  • General Biochemistry, Genetics and Molecular Biology


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