Noninvasive tumor volume measurement using magnetic resonance (MR) imaging and an open sided saddle coil.

J. L. Valentine, W. S. Yamanashi, A. A. Patil, R. Paulsen, D. L. Hill, P. D. Lester, O. F. Filip

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

A magnetic resonance (MR) imaging scanner operated at 0.5 T with a specially constructed receiving coil was used to measure volumes of primary spontaneous tumors in rats and guinea pigs. The coil was used to improve the signal to noise ratio (S/N) of the MR images of tumors in these small animals. The tumor volume was determined by the summation of the volume of contiguous slices or ellipsoid approximation. The accuracy of the volume measurement was better when the numerical integration was used in calculating the slice volume. The open sided saddle (OSS) coil used as the receiving coil gave better S/N than that of the standard head coil.

Original languageEnglish (US)
Pages (from-to)103-108
Number of pages6
JournalPhysiological chemistry and physics and medical NMR
Volume18
Issue number2
StatePublished - 1986

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Physiology
  • Spectroscopy

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