Nucleotide sequence of the 5′-flanking region of the mouse κ-FGF oncogene exhibits an alternating purine: pyrimidine motif with the potential to form Z-DNA

Jay Tiesman, Angie Rizzino

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

The nucleotide sequence of the 5′-flanking region of the mouse κ-FGF oncogene has been determined. This sequence extends 2.1 kb upstream from the transcriptional start point (tsp) and includes two Sp1 and two AP-2 consensus binding sequences immediately 5′ of the TATA box. In addition, the sequence contains an alternating purine: pyrimidine motif that lies approx. 1 kb upstream from the tsp.

Original languageEnglish (US)
Pages (from-to)311-312
Number of pages2
JournalGene
Volume96
Issue number2
DOIs
StatePublished - Dec 15 1990

Keywords

  • Recombinant DNA
  • consensus binding sequence
  • transcription factors AP-2 andSp1

ASJC Scopus subject areas

  • Genetics

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