The nucleotide sequence of the 5′-flanking region of the mouse κ-FGF oncogene has been determined. This sequence extends 2.1 kb upstream from the transcriptional start point (tsp) and includes two Sp1 and two AP-2 consensus binding sequences immediately 5′ of the TATA box. In addition, the sequence contains an alternating purine: pyrimidine motif that lies approx. 1 kb upstream from the tsp.
- Recombinant DNA
- consensus binding sequence
- transcription factors AP-2 andSp1
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