TY - JOUR
T1 - Nutrition Support of Children with Chronic Liver Diseases
T2 - A Joint Position Paper of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition
AU - Mouzaki, Marialena
AU - Bronsky, Jiri
AU - Gupte, Girish
AU - Hojsak, Iva
AU - Jahnel, Jorg
AU - Pai, Nikhil
AU - Quiros-Tejeira, Ruben E.
AU - Wieman, Renee
AU - Sundaram, Shikha
N1 - Publisher Copyright:
Copyright © 2019 ESPGHAN and NASPGHAN. All rights reserved.
PY - 2019/10/1
Y1 - 2019/10/1
N2 - Chronic liver disease places patients at increased risk of malnutrition that can be challenging to identify clinically and treat. Nutrition support is a key aspect of the management of these patients as it has an impact on their quality of life, morbidity, and mortality. There are significant gaps in the literature regarding the optimal nutrition support for patients with different types of liver diseases and the impact of these interventions on long-term outcomes. This Position Paper summarizes the available literature on the nutritional aspects of the care of patients with chronic liver diseases. Specifically, the challenges associated with the nutritional assessment of these subjects are discussed, and recently investigated approaches to determining the patients' nutritional status are reviewed. Furthermore, the pathophysiology of the malnutrition seen in the context of chronic liver disease is summarized and monitoring, as well as treatment, recommendations are provided. Lastly, suggestions for future research studies are described.
AB - Chronic liver disease places patients at increased risk of malnutrition that can be challenging to identify clinically and treat. Nutrition support is a key aspect of the management of these patients as it has an impact on their quality of life, morbidity, and mortality. There are significant gaps in the literature regarding the optimal nutrition support for patients with different types of liver diseases and the impact of these interventions on long-term outcomes. This Position Paper summarizes the available literature on the nutritional aspects of the care of patients with chronic liver diseases. Specifically, the challenges associated with the nutritional assessment of these subjects are discussed, and recently investigated approaches to determining the patients' nutritional status are reviewed. Furthermore, the pathophysiology of the malnutrition seen in the context of chronic liver disease is summarized and monitoring, as well as treatment, recommendations are provided. Lastly, suggestions for future research studies are described.
KW - cirrhosis
KW - frailty
KW - malnutrition
KW - metabolic bone disease
KW - nutrient deficiencies
UR - http://www.scopus.com/inward/record.url?scp=85072158557&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85072158557&partnerID=8YFLogxK
U2 - 10.1097/MPG.0000000000002443
DO - 10.1097/MPG.0000000000002443
M3 - Article
C2 - 31436707
AN - SCOPUS:85072158557
SN - 0277-2116
VL - 69
SP - 498
EP - 511
JO - Journal of pediatric gastroenterology and nutrition
JF - Journal of pediatric gastroenterology and nutrition
IS - 4
ER -