TY - JOUR
T1 - Obesity and chronic obstructive pulmonary disease
T2 - Recent knowledge and future directions
AU - Hanson, Corrine
AU - LeVan, Tricia
PY - 2017/3/1
Y1 - 2017/3/1
N2 - Purpose of review Obesity has been shown to have a significant impact on lung diseases, including chronic obstructive pulmonary disease (COPD). The purpose of this review is to discuss the most recent findings regarding the association between obesity, COPD, and COPD-related outcomes. Recent findings Evidence indicates that obese patients with COPD may compose a unique disease phenotype who are more susceptible than their lean counterparts to environmental exposures. The contribution of the visceral fat mass, irrespective of the total body fat mass, to the pathophysiology of COPD needs to be further explored in future studies. Summary Recent evidence supports a link between obesity and outcomes in COPD. Whether treatment of obesity also results in positive long-Term effects in patients with COPD needs further investigation.
AB - Purpose of review Obesity has been shown to have a significant impact on lung diseases, including chronic obstructive pulmonary disease (COPD). The purpose of this review is to discuss the most recent findings regarding the association between obesity, COPD, and COPD-related outcomes. Recent findings Evidence indicates that obese patients with COPD may compose a unique disease phenotype who are more susceptible than their lean counterparts to environmental exposures. The contribution of the visceral fat mass, irrespective of the total body fat mass, to the pathophysiology of COPD needs to be further explored in future studies. Summary Recent evidence supports a link between obesity and outcomes in COPD. Whether treatment of obesity also results in positive long-Term effects in patients with COPD needs further investigation.
KW - BMI
KW - body composition
KW - chronic obstructive pulmonary disease
KW - obesity
UR - http://www.scopus.com/inward/record.url?scp=85001019685&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85001019685&partnerID=8YFLogxK
U2 - 10.1097/MCP.0000000000000354
DO - 10.1097/MCP.0000000000000354
M3 - Review article
C2 - 27906857
AN - SCOPUS:85001019685
SN - 1070-5287
VL - 23
SP - 149
EP - 153
JO - Current Opinion in Pulmonary Medicine
JF - Current Opinion in Pulmonary Medicine
IS - 2
ER -