Ocular manifestations of systemic lupus erythematosus: A review of the literature

Neal V. Palejwala, Harpreet S. Walia, Steven Yeh

Research output: Contribution to journalReview articlepeer-review

152 Scopus citations


About one-third of patients suffering from systemic lupus erythematosus have ocular manifestations. The most common manifestation is keratoconjunctivitis sicca. The most vision threatening are retinal vasculitis and optic neuritis/neuropathy. Prompt diagnosis and treatment of eye disease is paramount as they are often associated with high levels of systemic inflammation and end-organ damage. Initial management with high-dose oral or IV corticosteroids is often necessary. Multiple steroid-sparing treatment options exist with the most recently studied being biologic agents.

Original languageEnglish (US)
Article number290898
JournalAutoimmune Diseases
Issue number1
StatePublished - 2012
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Immunology and Microbiology (miscellaneous)


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