On the origin of species: Insights from the ecological genomics of lake whitefish

Louis Bernatchez, Sébastien Renaut, Andrew R. Whiteley, Nicolas Derome, Julie Jeukens, Lysandre Landry, Guoqing Lu, Arne W. Nolte, Kjartan Østbye, Sean M. Rogers, Jérôme St-Cyr

Research output: Contribution to journalArticle

170 Scopus citations

Abstract

In contrast to the large amount of ecological information supporting the role of natural selection as a main cause of population divergence and speciation, an understanding of the genomic basis underlying those processes is in its infancy. In this paper, we review the main findings of a long-term research programme that we have been conducting on the ecological genomics of sympatric forms of whitefish (Coregonus spp.) engaged in the process of speciation. We present this system as an example of how applying a combination of approaches under the conceptual framework of the theory of adaptive radiation has yielded substantial insight into evolutionary processes in a non-model species. We also discuss how the joint use of recent biotechnological developments will provide a powerful means to address issues raised by observations made to date. Namely, we present data illustrating the potential offered by combining next generation sequencing technologies with other genomic approaches to reveal the genomic bases of adaptive divergence and reproductive isolation. Given increasing access to these new genomic tools, we argue that non-model species studied in their ecological context such as whitefish will play an increasingly important role in generalizing knowledge of speciation.

Original languageEnglish (US)
Pages (from-to)1783-1800
Number of pages18
JournalPhilosophical Transactions of the Royal Society B: Biological Sciences
Volume365
Issue number1547
DOIs
StatePublished - Jun 12 2010

Keywords

  • 454 sequencing
  • Ecological genomics
  • Microarrays
  • Selection
  • Speciation
  • Stickleback

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

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    Bernatchez, L., Renaut, S., Whiteley, A. R., Derome, N., Jeukens, J., Landry, L., Lu, G., Nolte, A. W., Østbye, K., Rogers, S. M., & St-Cyr, J. (2010). On the origin of species: Insights from the ecological genomics of lake whitefish. Philosophical Transactions of the Royal Society B: Biological Sciences, 365(1547), 1783-1800. https://doi.org/10.1098/rstb.2009.0274