One NOTCH Further: Jagged 1 in Bone Metastasis

Jianning Tao, Ayelet Erez, Brendan Lee

Research output: Contribution to journalShort surveypeer-review

10 Scopus citations

Abstract

The outgrowth of metastatic cells to bone depends on the interaction between multiple intrinsic and host factors. In this issue of Cancer Cell, Sethi and colleagues report Notch signaling in bone cells as responsible for promoting this outgrowth and provide evidence for a beneficial treatment effect of NOTCH inhibitors.

Original languageEnglish (US)
Pages (from-to)159-161
Number of pages3
JournalCancer Cell
Volume19
Issue number2
DOIs
StatePublished - Feb 15 2011
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cell Biology
  • Cancer Research

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