Opioid antagonists. I: Pharmacology and rationale for use in treating self-injury

Yadhu N. Singh; Robert W. Ricketts; Cynthia R. Ellis; Nirhay N. Singh

doi:10.1007/BF01046594

Opioid antagonists. I: Pharmacology and rationale for use in treating self-injury

Yadhu N. Singh, Robert W. Ricketts, Cynthia R. Ellis, Nirhay N. Singh

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Endogenous opioid peptides have been implicated in the genesis and maintenance of self-injurious behavior. This paper presents an overview of the basic pharmacology of opioid peptides and opioid antagonists and briefly outlines the rationale for using these agents to treat self-injury in individuals with mental retardation. The basic assumption is that self-injury is related to the endogenous opioid system, with two, nonexclusive mechanisms having been postulated that may account for this behavior.

Original language	English (US)
Pages (from-to)	5-15
Number of pages	11
Journal	Journal of Developmental and Physical Disabilities
Volume	5
Issue number	1
DOIs	https://doi.org/10.1007/BF01046594
State	Published - Mar 1993
Externally published	Yes

Keywords

opioid antagonists
pharmacology
self-injury

ASJC Scopus subject areas

Physical Therapy, Sports Therapy and Rehabilitation
Developmental and Educational Psychology

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10.1007/BF01046594

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abstract = "Endogenous opioid peptides have been implicated in the genesis and maintenance of self-injurious behavior. This paper presents an overview of the basic pharmacology of opioid peptides and opioid antagonists and briefly outlines the rationale for using these agents to treat self-injury in individuals with mental retardation. The basic assumption is that self-injury is related to the endogenous opioid system, with two, nonexclusive mechanisms having been postulated that may account for this behavior.",

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year = "1993",

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AB - Endogenous opioid peptides have been implicated in the genesis and maintenance of self-injurious behavior. This paper presents an overview of the basic pharmacology of opioid peptides and opioid antagonists and briefly outlines the rationale for using these agents to treat self-injury in individuals with mental retardation. The basic assumption is that self-injury is related to the endogenous opioid system, with two, nonexclusive mechanisms having been postulated that may account for this behavior.

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Opioid antagonists. I: Pharmacology and rationale for use in treating self-injury

Abstract

Keywords

ASJC Scopus subject areas

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