Optic neuritis: A novel presentation of Schilder's disease

Adel K. Afifi; Kenneth A. Follett; Jeremy Greenlee; William E. Scott; Steven A. Moore

doi:10.1177/088307380101600915

Optic neuritis: A novel presentation of Schilder's disease

Adel K. Afifi, Kenneth A. Follett, Jeremy Greenlee, William E. Scott, Steven A. Moore

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

The clinical features of a 7-year-old girl who presented with unilateral optic neuritis are presented. Magnetic resonance imaging (MRI) showed lesions in the affected optic nerve and the centrum semiovale bilaterally. Biopsy of one of the cerebral lesions was consistent with a diagnosis of Schilder's disease. Visual acuity returned to normal, and the demyelinating MRI lesions improved markedly with corticosteroid treatment. Optic neuritis is a novel mode of presentation in Schilder's disease.

Original language	English (US)
Pages (from-to)	693-696
Number of pages	4
Journal	Journal of Child Neurology
Volume	16
Issue number	9
DOIs	https://doi.org/10.1177/088307380101600915
State	Published - 2001
Externally published	Yes

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Clinical Neurology

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title = "Optic neuritis: A novel presentation of Schilder's disease",

abstract = "The clinical features of a 7-year-old girl who presented with unilateral optic neuritis are presented. Magnetic resonance imaging (MRI) showed lesions in the affected optic nerve and the centrum semiovale bilaterally. Biopsy of one of the cerebral lesions was consistent with a diagnosis of Schilder's disease. Visual acuity returned to normal, and the demyelinating MRI lesions improved markedly with corticosteroid treatment. Optic neuritis is a novel mode of presentation in Schilder's disease.",

author = "Afifi, {Adel K.} and Follett, {Kenneth A.} and Jeremy Greenlee and Scott, {William E.} and Moore, {Steven A.}",

year = "2001",

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AU - Afifi, Adel K.

AU - Follett, Kenneth A.

AU - Greenlee, Jeremy

AU - Scott, William E.

AU - Moore, Steven A.

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AB - The clinical features of a 7-year-old girl who presented with unilateral optic neuritis are presented. Magnetic resonance imaging (MRI) showed lesions in the affected optic nerve and the centrum semiovale bilaterally. Biopsy of one of the cerebral lesions was consistent with a diagnosis of Schilder's disease. Visual acuity returned to normal, and the demyelinating MRI lesions improved markedly with corticosteroid treatment. Optic neuritis is a novel mode of presentation in Schilder's disease.

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Optic neuritis: A novel presentation of Schilder's disease

Abstract

ASJC Scopus subject areas

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