Optic neuritis: A novel presentation of Schilder's disease

Adel K. Afifi, Kenneth A. Follett, Jeremy Greenlee, William E. Scott, Steven A. Moore

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


The clinical features of a 7-year-old girl who presented with unilateral optic neuritis are presented. Magnetic resonance imaging (MRI) showed lesions in the affected optic nerve and the centrum semiovale bilaterally. Biopsy of one of the cerebral lesions was consistent with a diagnosis of Schilder's disease. Visual acuity returned to normal, and the demyelinating MRI lesions improved markedly with corticosteroid treatment. Optic neuritis is a novel mode of presentation in Schilder's disease.

Original languageEnglish (US)
Pages (from-to)693-696
Number of pages4
JournalJournal of Child Neurology
Issue number9
StatePublished - 2001
Externally publishedYes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology


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