To report the visual outcomes and change in spherical aberration in the first cohort of eyes treated at the Cole Eye Institute using the FS200 laser (Alcon Laboratories Inc). A chart review was performed on 100 eyes targeted for emmetropia with wavefront-optimized femto-LASIK using the WaveLight Allegretto Wave Eye-Q (Alcon Laboratories Inc) and FS200 lasers. Patients were subdivided into low (< -3.00 D, n = 23), moderate (-3.00 to -6.00 D, n = 45), and high myopia (> -6.00 D, n = 2). Pre- and 3- to 9-month postoperative wavefront aberrometry and uncorrected distance visual acuity (UDVA) were compared. An increase was found in spherical aberration of 0.03 +/- 0.02 microm (P = .14) for low myopia, but decreases were found of 0.01 +/- 0.01 microm (P = .45) for moderate myopia and 0.02 +/- 0.04 microm (P = .48) for high myopia. An increase in coma was noted of 0.02 +/- 0.02 microm (P = .37), 0.04 +/- 0.02 microm (P = .02), and 0.11 +/- 0.04 microm (P = .01) for low, moderate, and high myopes, respectively. An increase was found in total higher order aberrations of 0.05 +/- 0.04 microm (P = .17), 0.04 +/- 0.01 microm (P = .01), and 0.11-0.03 microm (P = .01) for low, moderate, and high myopes, respectively. Uncorrected distance visual acuity of 20/15 and 20/20 was achieved in 70% and 91% of low myopes, 58% and 93% of moderate myopes, and 34% and 78% of high myopes, respectively. Wavefront-optimized femto-LASIK with the WaveLight Allegretto Wave Eye-Q and FS200 lasers achieved excellent postoperative UDVA outcomes, with no significant induction of spherical aberration at all refractive errors.
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