Optimizing intracellular signaling domains for CAR NK cells in HIV immunotherapy: a comprehensive review

Giorgio Zenere; Omalla Allan Olwenyi; Siddappa N. Byrareddy; Stephen E. Braun

doi:10.1016/j.drudis.2019.02.002

Optimizing intracellular signaling domains for CAR NK cells in HIV immunotherapy: a comprehensive review

Giorgio Zenere, Omalla Allan Olwenyi, Siddappa N. Byrareddy, Stephen E. Braun

Research output: Contribution to journal › Review article

1 Scopus citations

Abstract

CAR NK cell strategies can be optimized to enhance cytotoxic antiviral response against HIV-infected cells by combining NK-specific CAR signaling domains.

Original language	English (US)
Pages (from-to)	983-991
Number of pages	9
Journal	Drug Discovery Today
Volume	24
Issue number	4
DOIs	https://doi.org/10.1016/j.drudis.2019.02.002
State	Published - Apr 2019

ASJC Scopus subject areas

Pharmacology
Drug Discovery

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10.1016/j.drudis.2019.02.002

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Zenere, G., Olwenyi, O. A., Byrareddy, S. N., & Braun, S. E. (2019). Optimizing intracellular signaling domains for CAR NK cells in HIV immunotherapy: a comprehensive review. Drug Discovery Today, 24(4), 983-991. https://doi.org/10.1016/j.drudis.2019.02.002

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abstract = "CAR NK cell strategies can be optimized to enhance cytotoxic antiviral response against HIV-infected cells by combining NK-specific CAR signaling domains.",

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