Optimizing intracellular signaling domains for CAR NK cells in HIV immunotherapy: a comprehensive review

Giorgio Zenere; Omalla Allan Olwenyi; Siddappa N. Byrareddy; Stephen E. Braun

doi:10.1016/j.drudis.2019.02.002

Optimizing intracellular signaling domains for CAR NK cells in HIV immunotherapy: a comprehensive review

Giorgio Zenere, Omalla Allan Olwenyi, Siddappa N. Byrareddy, Stephen E. Braun

Research output: Contribution to journal › Review article › peer-review

18 Scopus citations

Abstract

CAR NK cell strategies can be optimized to enhance cytotoxic antiviral response against HIV-infected cells by combining NK-specific CAR signaling domains.

Original language	English (US)
Pages (from-to)	983-991
Number of pages	9
Journal	Drug Discovery Today
Volume	24
Issue number	4
DOIs	https://doi.org/10.1016/j.drudis.2019.02.002
State	Published - Apr 2019

ASJC Scopus subject areas

Pharmacology
Drug Discovery

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10.1016/j.drudis.2019.02.002

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title = "Optimizing intracellular signaling domains for CAR NK cells in HIV immunotherapy: a comprehensive review",

abstract = "CAR NK cell strategies can be optimized to enhance cytotoxic antiviral response against HIV-infected cells by combining NK-specific CAR signaling domains.",

author = "Giorgio Zenere and Olwenyi, {Omalla Allan} and Byrareddy, {Siddappa N.} and Braun, {Stephen E.}",

note = "Publisher Copyright: {\textcopyright} 2019",

year = "2019",

month = apr,

doi = "10.1016/j.drudis.2019.02.002",

language = "English (US)",

volume = "24",

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T2 - a comprehensive review

AU - Zenere, Giorgio

AU - Olwenyi, Omalla Allan

AU - Byrareddy, Siddappa N.

AU - Braun, Stephen E.

PY - 2019/4

Y1 - 2019/4

N2 - CAR NK cell strategies can be optimized to enhance cytotoxic antiviral response against HIV-infected cells by combining NK-specific CAR signaling domains.

AB - CAR NK cell strategies can be optimized to enhance cytotoxic antiviral response against HIV-infected cells by combining NK-specific CAR signaling domains.

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M3 - Review article

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Optimizing intracellular signaling domains for CAR NK cells in HIV immunotherapy: a comprehensive review

Abstract

ASJC Scopus subject areas

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