Organ-specific autoimmunity

Cecile King, Nora Sarvetnick

Research output: Contribution to journalArticlepeer-review

36 Scopus citations


The past year has seen advances in our understanding of the mechanisms that control the expression of organ-specific autoimmunity. Attempts to develop therapeutic strategies for the prevention of autoimmune disease have largely been based on deviation of the T-cell response away from an autoaggressive, pro-inflammatory Th 1 response. Manipulation of the cytokine environment at the site of antigen uptake or presentation, the source of endogenous antigen, costimulatory molecules or peptides processed and presented has yielded interesting results.

Original languageEnglish (US)
Pages (from-to)863-871
Number of pages9
JournalCurrent Opinion in Immunology
Issue number6
StatePublished - Dec 1997
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


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