Organic barn dust inhibits surfactant protein D production through protein kinase-c alpha dependent increase of GPR116

Agriculture & Biology

• surfactant proteins 100%
• barns 77%
• dust 66%
• protein kinases 63%
• protein kinase C 21%
• pulmonary surfactant associated proteins 17%
• lungs 15%
• immunologic receptors 13%
• peptidoglycans 10%
• surfactants 9%
• lipopolysaccharides 9%
• inflammation 8%
• animal models 8%
• epithelial cells 8%
• protein synthesis 7%
• cell lines 7%
• receptors 6%
• pathogens 5%

Medicine & Life Sciences

• Pulmonary Surfactant-Associated Protein D 96%
• Dust 71%
• Protein Kinases 61%
• Collectins 30%
• Protein Kinase C-alpha 25%
• glycoprotein 340 18%
• Pulmonary Surfactant-Associated Proteins 14%
• Peptidoglycan 11%
• Messenger RNA 10%
• Alveolar Epithelial Cells 10%
• Lung 10%
• Surface-Active Agents 9%
• Lipopolysaccharides 8%
• Occupational Groups 6%
• Cell Line 5%
• Inflammation 5%
• Proteins 3%

Chemical Compounds

• Dust 72%
• Surfactant 44%
• Protein 27%
• Lung Surfactant 10%
• Peptidoglycan 9%
• Signalling Molecule 9%
• Lipopolysaccharide 8%
• Reduction 3%
• Time 2%