Osteosarcoma of the larynx: Treatment outcomes and patterns of failure analysis

Nathan R. Bennion, Michael J. Baine, Timothy Malouff, Weining Zhen

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

The incidence of laryngeal sarcoma is exceedingly low with osteosarcomas of the larynx being rarer still, comprising less than 1% of all associated malignancies. To date, only 32 cases have been reported since this pathologic entity was first described in 1942. In this article, we discuss the most recent case of laryngeal osteosarcoma in a patient presenting with respiratory distress found to be due to a tumor mass arising from her cricoid cartilage. We further summarize current knowledge regarding the epidemiology, presentation, and diagnosis of this uncommon disease. Lastly, we synthesize all available information regarding treatment and outcomes of the 32 previously described cases of osteosarcoma of the larynx as well as the presently described case in an attempt to offer some insight regarding optimal treatment in future cases.

Original languageEnglish (US)
Article number6955
Pages (from-to)18-22
Number of pages5
JournalRare Tumors
Volume9
Issue number1
DOIs
StatePublished - Mar 24 2017

Keywords

  • Chemoradiation
  • Larynx
  • Osteosarcoma
  • Surgery

ASJC Scopus subject areas

  • Histology
  • Oncology

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