Outcome of percutaneous mitral balloon valvuloplasty: Comparison of the Inoue and retrograde non-transseptal techniques. A single-center experience

Ioannis Iakovou, Gregory Pavlides, Vasilios Voudris, George Athanassopoulos, George Karatasakis, Athanasios Manginas, Vasilios Vassilikos, George Kourgiannidis, Emmanouel Papadakis, Nikolaos Koutsogiannis, George Chatzigeorgiou, Dennis V. Cokkinos

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Introduction. The transseptal Inoue (IN) and to a lesser extent retrograde non-transseptal (RNT) techniques are established procedures for percutaneous mitral balloon valvuloplasty (PBMV) in patients with mitral stenosis. However, a head to head comparison of these two techniques, especially from a single center, has not yet been reported. Methods. Seventy-two consecutive patients (n = 35 IN and n = 37 RNT) underwent PMBV in our clinic from October 1993 to December 1999. All baseline and procedural characteristics were compared, as well as immediate and long-term outcomes (mean follow-up, 42 ± 12 months) of the patients. Results. Baseline characteristics were similar in the two groups. A successful immediate result was achieved in 91% of IN patients and 89% of RNT patients. After the PMBV, mitral valve area (MVA) increased from 1.04 ± 0.16 cm2 to 1.6 ± 0.3 cm2 and from 1.06 ± 0.23 cm2 to 1.55 ± 0.3 cm2 in the IN group and RNT group, respectively (p = NS). There was a higher percentage of mild mitral regurgitation (MR) after the RNT technique (p = 0.03). Mean fluoroscopy time was 31 ± 16 minutes in the IN group and 39 ± 11 minutes in the RNT group (p = 0.02). After discharge, major adverse cardiac events (MACE: mitral valve replacement, repeat PMBV) occurred in 3 patients (8%) patients in the IN group and 5 patients (13.5%) in the RNT group (p = NS). Follow-up echocardiographic evaluation revealed no significant changes regarding MVA in either group. Conclusions. The IN and RNT techniques are comparable regarding the achieved MVA, with slightly more frequent MR post-RNT PBMV. IN requires significantly less fluoroscopy time. MACE and event-free survival rates at follow-up were similar in the two groups.

Original languageEnglish (US)
Pages (from-to)522-526
Number of pages5
JournalJournal of Invasive Cardiology
Issue number9
StatePublished - Sep 2002


  • Mitral valvuloplasty
  • Percutaneous intervention
  • Technique

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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