Outcomes of noncardiotomy patients requiring postoperative extracorporeal membrane oxygenation

Harrison Lang, Mitchell Milanuk, John Brady, Karin Trujillo, Elizabeth Lyden, Helen Mari Merritt-Genore

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Background: The use of extracorporeal membrane oxygenation (ECMO) in the postoperative period has expanded to include a variety of noncardiotomy procedures. It is important to investigate outcomes for this uniquely ill subset of patients as currently published data on this subject is limited. Methods: All ECMO events at our institution from 2006 to 2017 were retrospectively considered. Patients were grouped into a postoperative noncardiotomy (PNC) cohort (n = 20) and a larger control cohort (n = 220). For additional analysis, the PNC cohort was further split into a liver transplant group (n = 4) and thoracic surgery group (n = 10). Basic demographics, medical history, type of operation performed, indication for support, and survival data were collected on all patients. Appropriate statistical analyses were performed and a P <.05 was considered statistically significant. Results: Twenty PNC-ECMO patients were identified. The indications for support were respiratory failure, cardiac arrest, and cardiogenic shock. PNC patient survival was similar to our control cohort, as well as extracorporeal life support organization (ELSO) published data with 55% weaning off ECMO and 50% surviving to discharge. Twelve-month predicted survival was 40%. Post thoracic surgical patients were reviewed, and their survival rates were similar to the larger control cohort as well. There were no survivors in the liver transplant group. Conclusions: Despite recent noncardiotomy surgery, patients who required ECMO for salvage in the postoperative period showed similar outcomes compared to our larger cohort and to published ELSO data, and reasonable long-term survival outcomes. This suggests that ECMO may be applied to a variety of postoperative settings with outcomes on par with nationally published results.

Original languageEnglish (US)
Pages (from-to)1444-1451
Number of pages8
JournalJournal of cardiac surgery
Volume35
Issue number7
DOIs
StatePublished - Jul 1 2020

Keywords

  • cardiovascular research
  • perfusion

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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    Lang, H., Milanuk, M., Brady, J., Trujillo, K., Lyden, E., & Merritt-Genore, H. M. (2020). Outcomes of noncardiotomy patients requiring postoperative extracorporeal membrane oxygenation. Journal of cardiac surgery, 35(7), 1444-1451. https://doi.org/10.1111/jocs.14598