TY - JOUR
T1 - Oxacycle synthesis via intramolecular reaction of carbanions and peroxides
AU - Willand-Charnley, Rachel
AU - Puffer, Benjamin W.
AU - Dussault, Patrick H.
PY - 2014/4/23
Y1 - 2014/4/23
N2 - The intramolecular reaction of dialkyl peroxides with carbanions, generated via chemoselective metal-heteroatom exchange or deprotonation, provides a new approach to cyclic ethers. Applied in tandem with C-C bond formation, the strategy enables a one-step annelation to form oxaospirocycles.
AB - The intramolecular reaction of dialkyl peroxides with carbanions, generated via chemoselective metal-heteroatom exchange or deprotonation, provides a new approach to cyclic ethers. Applied in tandem with C-C bond formation, the strategy enables a one-step annelation to form oxaospirocycles.
UR - http://www.scopus.com/inward/record.url?scp=84899539819&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84899539819&partnerID=8YFLogxK
U2 - 10.1021/ja5026276
DO - 10.1021/ja5026276
M3 - Article
C2 - 24702123
AN - SCOPUS:84899539819
SN - 0002-7863
VL - 136
SP - 5821
EP - 5823
JO - Journal of the American Chemical Society
JF - Journal of the American Chemical Society
IS - 16
ER -