Paramyxovirus infection in pigs with interstitial pneumonia and encephalitis in the United States

Bruce H. Janke, Prem S. Paul, John G. Landgraf, Patrick G. Halbur, Clark D. Huinker

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

In the last few years, newly recognized paramyxoviruses have been associated with severe disease in several animal species, including swine, as well as in human beings. Recently, a paramyxovirus was isolated from a swine herd in the northcentral United States that experienced an epizootic of respiratory and central nervous system disease. Affected pigs had interstitial pneumonia with necrotizing bronchiolitis and encephalitis characterized by lymphocytic perivasculitis and diffuse gliosis. Germ-free pigs inoculated with this isolate developed mild clinical illness and similar but less severe histopathologic lesions in lungs and brain.

Original languageEnglish (US)
Pages (from-to)428-433
Number of pages6
JournalJournal of Veterinary Diagnostic Investigation
Volume13
Issue number5
DOIs
StatePublished - 2001

ASJC Scopus subject areas

  • veterinary(all)

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