Pathogenesis of acute monocular blindness from leaking anterior communicating artery aneurysms: Report of six cases

Jane W. Chan, William F. Hoyt, William G. Ellis, Daryl Gress

Research output: Contribution to journalArticlepeer-review

37 Scopus citations

Abstract

This report describes six cases of leaking anterior communicating aneurysms, collected over 37 years, that caused acute monocular blindness. In two cases, surgical and pathologic evidence demonstrated the pathogenic mechanism: As the aneurysm enlarges, the down-pointing dome compresses the optic nerve from above and adheres to it. When the aneurysm ruptures through the adherent dome, it bleeds directly into the optic nerve, resulting in severe headache and monocular blindness. The other cases also suggest an alternative mechanism, namely, direct optic nerve compression by the aneurysm.

Original languageEnglish (US)
Pages (from-to)680-683
Number of pages4
JournalNeurology
Volume48
Issue number3
DOIs
StatePublished - Mar 1997
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Neurology

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