Pathophysiology roles and translational opportunities of miRNAs in lymphoma

Christine E. Cutucache

doi:10.1016/B978-0-12-822287-4.00010-4

Pathophysiology roles and translational opportunities of miRNAs in lymphoma

Christine E. Cutucache

Biology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

The role of miRNA in lymphoma remains to be fully elucidated. However, as we have observed from many hematological malignancies, the function of miRNA can directly affect tumorigenesis, disease progression, and pathophysiology. With improved understanding of miRNA, we can expand our diagnostic methods to improve the early identification of lymphoma, and ultimately inform prognostication to give patients clarity and a range of personalized treatment opportunities. This chapter highlights the incidence, prevalence, and existing data surrounding miRNA within lymphomas, with a special focus on B-cell lymphomas, diffuse large B-cell lymphoma, and splenic marginal zone lymphoma.

Original language	English (US)
Title of host publication	MicroRNA in Human Malignancies
Publisher	Elsevier
Pages	187-194
Number of pages	8
ISBN (Electronic)	9780128222874
ISBN (Print)	9780128232743
DOIs	https://doi.org/10.1016/B978-0-12-822287-4.00010-4
State	Published - Jan 1 2022

Keywords

B-cell
Lymphoma
Oncogenesis
Pathogenesis
Pathophysiology
miRNA

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1016/B978-0-12-822287-4.00010-4

Cite this

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AB - The role of miRNA in lymphoma remains to be fully elucidated. However, as we have observed from many hematological malignancies, the function of miRNA can directly affect tumorigenesis, disease progression, and pathophysiology. With improved understanding of miRNA, we can expand our diagnostic methods to improve the early identification of lymphoma, and ultimately inform prognostication to give patients clarity and a range of personalized treatment opportunities. This chapter highlights the incidence, prevalence, and existing data surrounding miRNA within lymphomas, with a special focus on B-cell lymphomas, diffuse large B-cell lymphoma, and splenic marginal zone lymphoma.

KW - B-cell

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KW - Oncogenesis

KW - Pathogenesis

KW - Pathophysiology

KW - miRNA

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BT - MicroRNA in Human Malignancies

PB - Elsevier

ER -

Pathophysiology roles and translational opportunities of miRNAs in lymphoma

Abstract

Keywords

ASJC Scopus subject areas

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