Pathophysiology roles and translational opportunities of miRNAs in lymphoma

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The role of miRNA in lymphoma remains to be fully elucidated. However, as we have observed from many hematological malignancies, the function of miRNA can directly affect tumorigenesis, disease progression, and pathophysiology. With improved understanding of miRNA, we can expand our diagnostic methods to improve the early identification of lymphoma, and ultimately inform prognostication to give patients clarity and a range of personalized treatment opportunities. This chapter highlights the incidence, prevalence, and existing data surrounding miRNA within lymphomas, with a special focus on B-cell lymphomas, diffuse large B-cell lymphoma, and splenic marginal zone lymphoma.

Original languageEnglish (US)
Title of host publicationMicroRNA in Human Malignancies
PublisherElsevier
Pages187-194
Number of pages8
ISBN (Electronic)9780128222874
ISBN (Print)9780128232743
DOIs
StatePublished - Jan 1 2022

Keywords

  • B-cell
  • Lymphoma
  • Oncogenesis
  • Pathogenesis
  • Pathophysiology
  • miRNA

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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