Performance of self-reported measures for periodontitis in rheumatoid arthritis and osteoarthritis

Brian W. Coburn, Harlan R. Sayles, Jeffrey B Payne, Robert S. Redman, Jeffery C. Markt, Mark W Beatty, Garth R. Griffiths, David J. McGowan, Ted R Mikuls

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

Background: This study evaluates the performance of self-report against the reference standard of clinically defined periodontitis in patients with rheumatoid arthritis (RA) and osteoarthritis (OA) after accounting for factors associated with periodontitis. Methods: Six self-report periodontitis questions were evaluated in patients with RA and OA. Questions were validated against a reference standard of severe and moderate-to-severe periodontitis based on full-mouth examination. Multivariable logistic regression was used to evaluate the performance of: 1) self-report alone; 2) age, sex, education, and smoking status; and 3) a combination of the above. Model performance was assessed using the c-statistic. Convergent validity of self-reported "bone loss/deep pockets" and "loose teeth" was assessed; associations of self-report with RA disease characteristics were explored. Results: Self-report performed similarly in RA and OA, with individual question specificity for periodontitis ≥68% and sensitivity from 9.8% to 45%. Question-only models yielded c-statistics of 0.66 to 0.72, whereas risk factor-only models yielded c-statistics of 0.74 to 0.79. The highest-performing models incorporated both self-report questions and periodontitis risk factors, with c-statistics ≥0.79. Greater radiographic alveolar bone loss was observed among participants reporting "bone loss/deep pockets" (P <0.001) and "loose teeth" (P <0.001). Among patients with RA, "loose teeth," but not other self-report items, was associated with rheumatoid factor positivity (P = 0.047) and higher disease activity (P <0.001). Conclusions: Patient self-report, when combined with other risk factors, performs well in identifying periodontitis among patients with RA and OA. Self-report questions related to alveolar bone loss exhibit excellent convergent validity in these patient subsets.

Original languageEnglish (US)
Pages (from-to)16-26
Number of pages11
JournalJournal of periodontology
Volume86
Issue number1
DOIs
StatePublished - Jan 1 2015

Keywords

  • Arthritis
  • Osteoarthritis
  • Periodontitis
  • Rheumatoid
  • Rheumatoid factor
  • Self report
  • Sensitivity and specificity

ASJC Scopus subject areas

  • Periodontics

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