Peripherally cross-linking the shell of core-shell polymer micelles decreases premature release of physically loaded combretastatin A4 in whole blood and increases its mean residence time and subsequent potency against primary murine breast tumors after IV administration

Rajesh R. Wakaskar, Sai Praneeth R. Bathena, Shailendra B. Tallapaka, Vishakha V. Ambardekar, Nagsen Gautam, Rhishikesh Thakare, Samantha M. Simet, Stephen M. Curran, Rakesh K. Singh, Yuxiang Dong, Joseph A. Vetro

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Pharmacology, Toxicology and Pharmaceutical Science

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