Persistent intermediate uveitis associated with latent manifestation of facial large b-cell non-hodgkin lymphoma

E. Jason Sabet-Peyman; Charles G. Eberhart; Kashif Janjua; Syed Mahmood Shah; Diana V. Do; Quan Dong Nguyen

doi:10.3109/09273940903043048

Persistent intermediate uveitis associated with latent manifestation of facial large b-cell non-hodgkin lymphoma

E. Jason Sabet-Peyman, Charles G. Eberhart, Kashif Janjua, Syed Mahmood Shah, Diana V. Do, Quan Dong Nguyen

Ophthalmology and Visual Sciences

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Purpose: To report a case of intraocular non-Hodgkin lymphoma (NHL) manifesting as persistent intermediate uveitis, facial mass, and Bell palsy. Design: Retrospective, interventional case report. Methods: A 51-year-old patient with persistent intermediate uveitis for 4 years is diagnosed with intraocular NHL after developing Bell palsy and a facial mass. Initial diagnostic vitrectomy was inconclusive. Results: Subsequent treatment with cyclophosphamide, adriamycin, vincristine, prednisone, and rituximab resulted in regressed facial mass and improved visual acuity. Conclusion: NHL can manifest as latent Bell palsy and facial mass in addition to the more common symptoms of uveitis. Intraocular NHL should be suspected in any patient of any age with persistent uveitis.

Original language	English (US)
Pages (from-to)	322-324
Number of pages	3
Journal	Ocular Immunology and Inflammation
Volume	17
Issue number	5
DOIs	https://doi.org/10.3109/09273940903043048
State	Published - Oct 2009

Keywords

B-cell
Bell palsy
Facial mass
Intermediate uveitis
Lymphoma
Non-Hodgkin

ASJC Scopus subject areas

Immunology and Allergy
Ophthalmology

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10.3109/09273940903043048

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title = "Persistent intermediate uveitis associated with latent manifestation of facial large b-cell non-hodgkin lymphoma",

abstract = "Purpose: To report a case of intraocular non-Hodgkin lymphoma (NHL) manifesting as persistent intermediate uveitis, facial mass, and Bell palsy. Design: Retrospective, interventional case report. Methods: A 51-year-old patient with persistent intermediate uveitis for 4 years is diagnosed with intraocular NHL after developing Bell palsy and a facial mass. Initial diagnostic vitrectomy was inconclusive. Results: Subsequent treatment with cyclophosphamide, adriamycin, vincristine, prednisone, and rituximab resulted in regressed facial mass and improved visual acuity. Conclusion: NHL can manifest as latent Bell palsy and facial mass in addition to the more common symptoms of uveitis. Intraocular NHL should be suspected in any patient of any age with persistent uveitis.",

keywords = "B-cell, Bell palsy, Facial mass, Intermediate uveitis, Lymphoma, Non-Hodgkin",

author = "Sabet-Peyman, {E. Jason} and Eberhart, {Charles G.} and Kashif Janjua and Shah, {Syed Mahmood} and Do, {Diana V.} and Nguyen, {Quan Dong}",

year = "2009",

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language = "English (US)",

volume = "17",

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journal = "Ocular Immunology and Inflammation",

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AU - Sabet-Peyman, E. Jason

AU - Eberhart, Charles G.

AU - Janjua, Kashif

AU - Shah, Syed Mahmood

AU - Do, Diana V.

AU - Nguyen, Quan Dong

PY - 2009/10

Y1 - 2009/10

N2 - Purpose: To report a case of intraocular non-Hodgkin lymphoma (NHL) manifesting as persistent intermediate uveitis, facial mass, and Bell palsy. Design: Retrospective, interventional case report. Methods: A 51-year-old patient with persistent intermediate uveitis for 4 years is diagnosed with intraocular NHL after developing Bell palsy and a facial mass. Initial diagnostic vitrectomy was inconclusive. Results: Subsequent treatment with cyclophosphamide, adriamycin, vincristine, prednisone, and rituximab resulted in regressed facial mass and improved visual acuity. Conclusion: NHL can manifest as latent Bell palsy and facial mass in addition to the more common symptoms of uveitis. Intraocular NHL should be suspected in any patient of any age with persistent uveitis.

AB - Purpose: To report a case of intraocular non-Hodgkin lymphoma (NHL) manifesting as persistent intermediate uveitis, facial mass, and Bell palsy. Design: Retrospective, interventional case report. Methods: A 51-year-old patient with persistent intermediate uveitis for 4 years is diagnosed with intraocular NHL after developing Bell palsy and a facial mass. Initial diagnostic vitrectomy was inconclusive. Results: Subsequent treatment with cyclophosphamide, adriamycin, vincristine, prednisone, and rituximab resulted in regressed facial mass and improved visual acuity. Conclusion: NHL can manifest as latent Bell palsy and facial mass in addition to the more common symptoms of uveitis. Intraocular NHL should be suspected in any patient of any age with persistent uveitis.

KW - B-cell

KW - Bell palsy

KW - Facial mass

KW - Intermediate uveitis

KW - Lymphoma

KW - Non-Hodgkin

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Persistent intermediate uveitis associated with latent manifestation of facial large b-cell non-hodgkin lymphoma

Abstract

Keywords

ASJC Scopus subject areas

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