TY - JOUR
T1 - pH-Induced cucurbit[7]uril hydrogels
T2 - Understanding microenvironment of the aggregates through excited state reactivity of dibenzyl ketones
AU - Pattabiraman, Mahesh
AU - Maddipatla, Murthy V S N
AU - Ramamurthy, V.
N1 - Publisher Copyright:
© 2016 Elsevier B.V. All rights reserved.
PY - 2016/6/30
Y1 - 2016/6/30
N2 - The supramolecular chemistry of cucurbituril aggregates arising from peripheral interactions to form hydrogels is a relatively new and less explored aspect of the cavitand family. The hydrogels formed by cucurbit[7]uril (CB7) in aqueous media is understood to consist of CB7 networks linked through C - Ha⋯O interactions with readily manipulable material and mechanical properties, and is envisioned to contain high application potential. Therefore, understanding the microenvironmental properties of this newly emerging CB-based hydrogels is important. In this reported study we present our understanding about the microenvironmental characteristics of the CB7 hydrogels inferred from (a) the modified photoreactivity of non-C2-symmetric dibenzyl ketones (DBK) encapsulated within the hydrogels, and (b) NMR diffusion experiments. Reaction selectivity in DBK photochemistry offered insight regarding the structural integrity and effects of pH, temperature, and concentration on the aggregates, while the diffusion studies were useful in developing a qualitative idea about the equilibrium dynamics of the CB7 aggregates that constitute the hydrogels.
AB - The supramolecular chemistry of cucurbituril aggregates arising from peripheral interactions to form hydrogels is a relatively new and less explored aspect of the cavitand family. The hydrogels formed by cucurbit[7]uril (CB7) in aqueous media is understood to consist of CB7 networks linked through C - Ha⋯O interactions with readily manipulable material and mechanical properties, and is envisioned to contain high application potential. Therefore, understanding the microenvironmental properties of this newly emerging CB-based hydrogels is important. In this reported study we present our understanding about the microenvironmental characteristics of the CB7 hydrogels inferred from (a) the modified photoreactivity of non-C2-symmetric dibenzyl ketones (DBK) encapsulated within the hydrogels, and (b) NMR diffusion experiments. Reaction selectivity in DBK photochemistry offered insight regarding the structural integrity and effects of pH, temperature, and concentration on the aggregates, while the diffusion studies were useful in developing a qualitative idea about the equilibrium dynamics of the CB7 aggregates that constitute the hydrogels.
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U2 - 10.1016/j.jphotochem.2016.03.004
DO - 10.1016/j.jphotochem.2016.03.004
M3 - Article
AN - SCOPUS:84961917703
SN - 1010-6030
VL - 324
SP - 53
EP - 61
JO - Journal of Photochemistry and Photobiology A: Chemistry
JF - Journal of Photochemistry and Photobiology A: Chemistry
ER -