Abstract
Pharmacogenomics is the study of the role of genetic variations in drug response. In the study of pharmacogenomics, one can relate variations in drug exposure and/or drug response (pharmacology) to the variations in genes (genomics). An administered drug may fail to work for one patient, but show the expected result for another. In some cases a drug may work well for a larger group of patients, while causing a subset of patients to experience unexpected or severe side effects. These adverse drug reactions can be harmful and sometimes deadly. Factors such as the environment, diet, age, lifestyle and co-morbid conditions all may influence the individual’s response to drugs. Each is covered in this chapter with an eye towards how best to administer drug to individual patients.
Original language | English (US) |
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Title of host publication | Neuroimmune Pharmacology |
Publisher | Springer International Publishing |
Pages | 959-970 |
Number of pages | 12 |
ISBN (Electronic) | 9783319440224 |
ISBN (Print) | 9783319440200 |
DOIs | |
State | Published - Jan 1 2016 |
Keywords
- Gene variants
- Metabolizers
- Neurodegenerative
- Pharmacogenomics
ASJC Scopus subject areas
- General Immunology and Microbiology
- General Pharmacology, Toxicology and Pharmaceutics
- General Neuroscience
- General Medicine