Pharmacological activities of crude acetone extract and purified constituents of Salvia moorcraftiana Wall

T. Khan, M. Zahid, M. Asim, Shahzad-ul-Hussan, Z. Iqbal, M. Iqbal Choudhary, V. Uddin Ahmad

Research output: Contribution to journalArticle

25 Scopus citations

Abstract

The crude acetone extract of aerial parts of Salvia moorcraftiana Wall. was screened for various biological activities including Lemna bioassay, antifungal, antibacterial, leishmanicidal, insecticidal activities and brine shrimp cytotoxicity. It was found to possess strong phytotoxic activity against Lemna aequinoctials Welve. and moderate antifungal activity against animal and plant pathogens. The purified chemical constituents were tested for enzyme inhibition activity. Two constituents (compounds 3 and 8) were found to be effective inhibitors of α-glucosidase.

Original languageEnglish (US)
Pages (from-to)749-752
Number of pages4
JournalPhytomedicine
Volume9
Issue number8
DOIs
StatePublished - Dec 2002

Keywords

  • Antifungal activity
  • Enzyme inhibition activity
  • Phytotoxicity
  • Salvia moorcraftiana

ASJC Scopus subject areas

  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine

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