Pharmacology of aqueous humor formation

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations


Ocular aqueous humor circulation and drainage are essential in maintaining intraocular pressure and keeping avascular tissues of the anterior segment healthy. Slowing aqueous flow decreases intraocular pressure and provides a means of treating glaucoma. The classes of drugs that reduce aqueous flow are beta (β) blockers, carbonic anhydrase inhibitors, alpha-2 (α2) adrenergic agonists, and other sympathomimetics. These drugs work by different mechanisms to achieve the same effect. Stimulating aqueous flow increases intraocular pressure and may provide a means of treating hypotony. Effective aqueous flow stimulants remain elusive. Aqueous humor production and the pharmacological ways to alter it are the topics of this article.

Original languageEnglish (US)
Title of host publicationEncyclopedia of the Eye, Four-Volume Set
Number of pages4
ISBN (Electronic)9780123742032
ISBN (Print)9780123741981
StatePublished - Jan 1 2010


  • Aqueous flow
  • Aqueous production
  • Carbonic anhydrase inhibitors
  • Glaucoma
  • IOP
  • Inflow drugs
  • Sympathomimetics
  • β-blockers

ASJC Scopus subject areas

  • Medicine(all)

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