Pharmacology of aqueous humor formation

C. B. Toris

doi:10.1016/B978-0-12-374203-2.00091-9

Pharmacology of aqueous humor formation

C. B. Toris

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2 Scopus citations

Abstract

Ocular aqueous humor circulation and drainage are essential in maintaining intraocular pressure and keeping avascular tissues of the anterior segment healthy. Slowing aqueous flow decreases intraocular pressure and provides a means of treating glaucoma. The classes of drugs that reduce aqueous flow are beta (β) blockers, carbonic anhydrase inhibitors, alpha-2 (α₂) adrenergic agonists, and other sympathomimetics. These drugs work by different mechanisms to achieve the same effect. Stimulating aqueous flow increases intraocular pressure and may provide a means of treating hypotony. Effective aqueous flow stimulants remain elusive. Aqueous humor production and the pharmacological ways to alter it are the topics of this article.

Original language	English (US)
Title of host publication	Encyclopedia of the Eye, Four-Volume Set
Publisher	Elsevier
Pages	312-315
Number of pages	4
ISBN (Electronic)	9780123742032
ISBN (Print)	9780123741981
DOIs	https://doi.org/10.1016/B978-0-12-374203-2.00091-9
State	Published - Jan 1 2010
Externally published	Yes

Keywords

Aqueous flow
Aqueous production
Carbonic anhydrase inhibitors
Glaucoma
IOP
Inflow drugs
Sympathomimetics
β-blockers

ASJC Scopus subject areas

General Medicine

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10.1016/B978-0-12-374203-2.00091-9

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abstract = "Ocular aqueous humor circulation and drainage are essential in maintaining intraocular pressure and keeping avascular tissues of the anterior segment healthy. Slowing aqueous flow decreases intraocular pressure and provides a means of treating glaucoma. The classes of drugs that reduce aqueous flow are beta (β) blockers, carbonic anhydrase inhibitors, alpha-2 (α2) adrenergic agonists, and other sympathomimetics. These drugs work by different mechanisms to achieve the same effect. Stimulating aqueous flow increases intraocular pressure and may provide a means of treating hypotony. Effective aqueous flow stimulants remain elusive. Aqueous humor production and the pharmacological ways to alter it are the topics of this article.",

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AB - Ocular aqueous humor circulation and drainage are essential in maintaining intraocular pressure and keeping avascular tissues of the anterior segment healthy. Slowing aqueous flow decreases intraocular pressure and provides a means of treating glaucoma. The classes of drugs that reduce aqueous flow are beta (β) blockers, carbonic anhydrase inhibitors, alpha-2 (α2) adrenergic agonists, and other sympathomimetics. These drugs work by different mechanisms to achieve the same effect. Stimulating aqueous flow increases intraocular pressure and may provide a means of treating hypotony. Effective aqueous flow stimulants remain elusive. Aqueous humor production and the pharmacological ways to alter it are the topics of this article.

KW - Aqueous flow

KW - Aqueous production

KW - Carbonic anhydrase inhibitors

KW - Glaucoma

KW - IOP

KW - Inflow drugs

KW - Sympathomimetics

KW - β-blockers

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SN - 9780123741981

SP - 312

EP - 315

BT - Encyclopedia of the Eye, Four-Volume Set

PB - Elsevier

ER -

Pharmacology of aqueous humor formation

Abstract

Keywords

ASJC Scopus subject areas

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