Phenacetin abuse and renal pelvic carcinoma

U. Bengtsson, L. Angervall, S. Johansson, L. Wahlgvist

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


This work is a review of 62 patients with abuse of phenacetin containing drugs and uroepithelial tumors of the renal pelvis, all of them carcinomas. Most of the patients had a preexisting nephropathy with papillary necrosis as a prominent feature. Renal impairment contributed to the poor prognosis. On the basis of present knowledge of urinary tract carcinogens and phenacetin metabolites, it is assumed that phenacetin is the crucial factor for development of the tumours.

Original languageEnglish (US)
Pages (from-to)290-294
Number of pages5
JournalInternational Journal of Clinical Pharmacology Therapy and Toxicology
Issue number1-2
StatePublished - 1975
Externally publishedYes

ASJC Scopus subject areas

  • Toxicology
  • Pharmacology (medical)


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