The in vitro effects of phosphatidyl choline, phosphatidyl ethanolamine, phosphatidyl serine, sphingomyelin, lysophosphatidyl choline, lysophosphatidyl ethanolamine, lysophosphatidyl serine, glycerophosphoryl choline, and phosphatidic acid on rubidium uptake and amino acid transport of rat lens are presented. None of these lipids affected the rubidium uptake mechanism; however, a large increase in the apparent leak-out of rubidium was observed with lysophosphatidyl choline. Lysophosphatidyl choline also inhibited all of the amino acid transport systems (A, ASC, L, Gly, Ly and β) as well as the uptake of inositol.
- amino acid transport inhibition
- lysophosphatidyl choline
- rubidium transport
ASJC Scopus subject areas
- Sensory Systems
- Cellular and Molecular Neuroscience