Physiological Bone Remodeling: Systemic Regulation and Growth Factor Involvement.

Jawed A Siddiqui

doi:10.1152/physiol.00061.2014

Physiological Bone Remodeling: Systemic Regulation and Growth Factor Involvement.

Jawed A Siddiqui

Biochemistry & Molecular Biology

Research output: Contribution to journal › Article › peer-review

378 Scopus citations

Abstract

Bone remodeling is essential for adult bone homeostasis. It comprises two phases: bone formation and resorption. The balance between the two phases is crucial for sustaining bone mass and systemic mineral homeostasis. This review highlights recent work on physiological bone remodeling and discusses our knowledge of how systemic and growth factors regulate this process.

Original language	English (US)
Journal	Physiology (Bethesda, Md.)
DOIs	https://doi.org/10.1152/physiol.00061.2014
State	Published - May 1 2016

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abstract = "Bone remodeling is essential for adult bone homeostasis. It comprises two phases: bone formation and resorption. The balance between the two phases is crucial for sustaining bone mass and systemic mineral homeostasis. This review highlights recent work on physiological bone remodeling and discusses our knowledge of how systemic and growth factors regulate this process.",

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AB - Bone remodeling is essential for adult bone homeostasis. It comprises two phases: bone formation and resorption. The balance between the two phases is crucial for sustaining bone mass and systemic mineral homeostasis. This review highlights recent work on physiological bone remodeling and discusses our knowledge of how systemic and growth factors regulate this process.

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Physiological Bone Remodeling: Systemic Regulation and Growth Factor Involvement.

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