Physiological doses of Epinephrine in the human: Chronotropic but not hyperglycemic or catecholaminotropic

August Epple, John M. Bertoni, Charles B. Hathaway

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Single physiological doses of epinephrine did not affect the blood sugar level of human volunteers though they caused a marked tachycardia that was accompanied by a strong transient sensation, typically described as fullness in the chest. Epinephrine did not cause the release of norepinephrine and/or dopamine in man, in contrast to three other vertebrates (lamprey, eel, and rat). In the human, as in the rat and cyclostomes, the glycemic effect of epinephrine occurs only during stress and/or unphysiological conditions, while the chronotropic effects are probably physiological from cyclostomes to man.

Original languageEnglish (US)
Pages (from-to)67-72
Number of pages6
JournalJournal of Experimental Zoology
Volume250
Issue number1
DOIs
StatePublished - Apr 1989

ASJC Scopus subject areas

  • Animal Science and Zoology

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