Physiological role of NBCe2 in the regulation of electrolyte transport in the distal nephron

Donghai Wen; Steven C. Sansom

doi:10.1152/ajprenal.00192.2015

Physiological role of NBCe2 in the regulation of electrolyte transport in the distal nephron

Donghai Wen, Steven C. Sansom

Cellular & Integrative Physiology

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

Abstract

The electrogenic Na⁺-HCO₃^–cotransporter 2 (NBCe2) is a newly discovered protein in the distal nephron. Our understanding is minimal regarding its physiological role in renal electrolyte transport. In this mini-review, we summarize the potential function of NBCe2 in the regulation of blood pressure, acid-base, and K⁺ and Ca²⁺ transport in the distal nephron.

Original language	English (US)
Pages (from-to)	F489-F491
Journal	American Journal of Physiology - Renal Physiology
Volume	309
Issue number	6
DOIs	https://doi.org/10.1152/ajprenal.00192.2015
State	Published - Sep 15 2015

Keywords

Acid-base
Ca
Hypertension
K
NBCe2

ASJC Scopus subject areas

Physiology
Urology

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10.1152/ajprenal.00192.2015

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title = "Physiological role of NBCe2 in the regulation of electrolyte transport in the distal nephron",

abstract = "The electrogenic Na+-HCO3–cotransporter 2 (NBCe2) is a newly discovered protein in the distal nephron. Our understanding is minimal regarding its physiological role in renal electrolyte transport. In this mini-review, we summarize the potential function of NBCe2 in the regulation of blood pressure, acid-base, and K+ and Ca2+ transport in the distal nephron.",

keywords = "Acid-base, Ca, Hypertension, K, NBCe2",

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AU - Sansom, Steven C.

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AB - The electrogenic Na+-HCO3–cotransporter 2 (NBCe2) is a newly discovered protein in the distal nephron. Our understanding is minimal regarding its physiological role in renal electrolyte transport. In this mini-review, we summarize the potential function of NBCe2 in the regulation of blood pressure, acid-base, and K+ and Ca2+ transport in the distal nephron.

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KW - Ca

KW - Hypertension

KW - K

KW - NBCe2

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Physiological role of NBCe2 in the regulation of electrolyte transport in the distal nephron

Abstract

Keywords

ASJC Scopus subject areas

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