Physostigmine reversal of diazepam induced depression

G. F. Larson; B. J. Hurlbert; D. W. Wingard

doi:10.1213/00000539-197705000-00006

Physostigmine reversal of diazepam induced depression

G. F. Larson, B. J. Hurlbert, D. W. Wingard

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

Abstract

Diazepam is a valuable and widely-used adjunct to many inpatient and outpatient diagnostic and therapeutic procedures. However, the occasional and often unexpected delirium or coma induced by even modest doses of diazepam can be life threatening. 4 cases are reported which demonstrate the prompt and effective reversal of diazepam-induced delirium and coma by the administration of physostigmine.

Original language	English (US)
Pages (from-to)	348-351
Number of pages	4
Journal	Anesthesia and analgesia
Volume	56
Issue number	3
DOIs	https://doi.org/10.1213/00000539-197705000-00006
State	Published - 1977
Externally published	Yes

ASJC Scopus subject areas

Anesthesiology and Pain Medicine

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title = "Physostigmine reversal of diazepam induced depression",

abstract = "Diazepam is a valuable and widely-used adjunct to many inpatient and outpatient diagnostic and therapeutic procedures. However, the occasional and often unexpected delirium or coma induced by even modest doses of diazepam can be life threatening. 4 cases are reported which demonstrate the prompt and effective reversal of diazepam-induced delirium and coma by the administration of physostigmine.",

author = "Larson, {G. F.} and Hurlbert, {B. J.} and Wingard, {D. W.}",

year = "1977",

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AU - Hurlbert, B. J.

AU - Wingard, D. W.

PY - 1977

Y1 - 1977

N2 - Diazepam is a valuable and widely-used adjunct to many inpatient and outpatient diagnostic and therapeutic procedures. However, the occasional and often unexpected delirium or coma induced by even modest doses of diazepam can be life threatening. 4 cases are reported which demonstrate the prompt and effective reversal of diazepam-induced delirium and coma by the administration of physostigmine.

AB - Diazepam is a valuable and widely-used adjunct to many inpatient and outpatient diagnostic and therapeutic procedures. However, the occasional and often unexpected delirium or coma induced by even modest doses of diazepam can be life threatening. 4 cases are reported which demonstrate the prompt and effective reversal of diazepam-induced delirium and coma by the administration of physostigmine.

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ER -

Physostigmine reversal of diazepam induced depression

Abstract

ASJC Scopus subject areas

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